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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DNM2
All Species:
27.58
Human Site:
T109
Identified Species:
67.41
UniProt:
P50570
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50570
NP_001005360.1
870
98064
T109
E
A
E
T
D
R
V
T
G
T
N
K
G
I
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001103119
870
98099
T109
E
A
E
T
D
R
V
T
G
T
N
K
G
I
S
Dog
Lupus familis
XP_542065
865
97464
T109
E
A
E
T
D
R
V
T
G
T
N
K
G
I
S
Cat
Felis silvestris
Mouse
Mus musculus
P39054
870
98127
T109
E
A
E
T
D
R
V
T
G
T
N
K
G
I
S
Rat
Rattus norvegicus
P39052
870
98212
T109
E
A
E
T
D
R
V
T
G
T
N
K
G
I
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7SXN5
691
77244
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P27619
877
97791
T104
E
D
E
T
D
R
V
T
G
S
N
K
G
I
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P39055
830
93389
T111
E
D
E
T
D
R
V
T
G
Q
N
K
G
I
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LFT2
780
86625
L85
R
R
P
L
R
L
Q
L
V
Q
T
K
P
S
S
Baker's Yeast
Sacchar. cerevisiae
P54861
757
84953
T62
P
R
G
T
G
I
V
T
R
R
P
L
V
L
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.7
95.1
N.A.
98.1
98
N.A.
N.A.
N.A.
N.A.
32.9
N.A.
64.4
N.A.
61.9
N.A.
Protein Similarity:
100
N.A.
100
97.2
N.A.
99
99.1
N.A.
N.A.
N.A.
N.A.
51
N.A.
76.9
N.A.
76.5
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
0
N.A.
86.6
N.A.
86.6
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
0
N.A.
93.3
N.A.
86.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.5
35.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.5
54.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
50
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
20
0
0
70
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
70
0
70
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
10
0
0
0
70
0
0
0
70
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
0
0
0
70
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
80
0
0
0
% K
% Leu:
0
0
0
10
0
10
0
10
0
0
0
10
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
70
0
0
0
0
% N
% Pro:
10
0
10
0
0
0
0
0
0
0
10
0
10
0
0
% P
% Gln:
0
0
0
0
0
0
10
0
0
20
0
0
0
0
10
% Q
% Arg:
10
20
0
0
10
70
0
0
10
10
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
80
% S
% Thr:
0
0
0
80
0
0
0
80
0
50
10
0
0
0
0
% T
% Val:
0
0
0
0
0
0
80
0
10
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _